Advancing B Cell Depletion Without T-Cells: Leveraging GEM-DIMER Technology to Mitigate Cytokine Toxicity in Autoimmunity
Time: 11:30 am
Details:
- Designing T-cell-independent bispecifics for autoimmune B cell depletion to avoid key TCE-associated liabilities
- Demonstrating potent B cell depletion and favourable safety in NHP in vivo
- Positioning for autoimmune indications where reduced cytokine release is essential for patient tolerability
