Juha Punnonen
Seminars
Thursday 16th October 2025
Advancing B Cell Depletion Without T-Cells: Leveraging GEM-DIMER Technology to Mitigate Cytokine Toxicity in Autoimmunity
11:30 am
- Designing T-cell-independent bispecifics for autoimmune B cell depletion to avoid key TCE-associated liabilities
- Demonstrating potent B cell depletion and favourable safety in NHP in vivo
- Positioning for autoimmune indications where reduced cytokine release is essential for patient tolerability
Thursday 16th October 2025
Advancing B Cell Depletion Without T-Cells: Leveraging GEM-DIMER Technology to Mitigate Cytokine Toxicity in Autoimmunity
11:30 am
- Designing T-cell-independent bispecifics for autoimmune B cell depletion to avoid key TCE-associated liabilities
- Demonstrating potent B cell depletion and favourable safety in NHP in vivo
- Positioning for autoimmune indications where reduced cytokine release is essential for patient tolerability
