Kate Rochlin

Company: IN8Bio

Job title: Chief Operating Officer

Seminars:

Activating the Potential of Gamma Delta T-Cells in Preclinical Models: A Next-Generation Strategy to Minimize CRS & Rethink TCE Safety in Autoimmunity 1:00 pm

Introduction to the potential of gamma delta T-cells and tackling the challenge of their limited presence in patients by engineering engagers that expand and activate these cells in vivo without relying on CD3 stimulation Exploring ways to safely increase levels of rare immune cells like gamma delta T-cells and NK cells inside the body for…Read more

day: Day Two

Panel Discussion: Investigating Preclinical Platforms for Autoimmune T-Cell Engagers From Human Relevant Assays to Regulatory Confidence 2:40 pm

For TCEs in autoimmunity, conventional preclinical tools, often adapted from oncology, fall short in capturing the inflammatory, chronic, and tissue-specific nature of disease. This panel will explore how to build assays that reflect real autoimmune biology, capture safety-relevant signals, and avoid reliance on transgenic animals. With human target expression and immune context being essential, developers…Read more

day: Day Two