Optimizing Multi-Targeted Immune Cell Depletion with FP014 to Enhance Therapeutic Window, Efficacy & Long-Term Disease Control
- Evaluating how simultaneous targeting of multiple B-cell populations through a trispecific approach can improve the depth and consistency of immune-cell depletion while reducing the risk of disease persistence and target escape
- Characterizing the relationship between target engagement, cytokine release, immune-cell depletion kinetics, and safety outcomes to identify strategies that maximize therapeutic benefit while minimizing toxicity
- Leveraging de novo engineered T-cell toolbox and platform to enable faster and safer deployment of next generation TCE molecules in autoimmune disease